Gonadorelin 2mg
Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH), a naturally occurring peptide that plays a critical role in regulating the reproductive endocrine system. It is primarily used in research to study the hypothalamic-pituitary-gonadal (HPG) axis and its influence on luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion. Gonadorelin is ideal for exploring hormonal regulation, fertility, and pituitary function.
Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH), a naturally occurring peptide that plays a critical role in regulating the reproductive endocrine system. It is primarily used in research to study the hypothalamic-pituitary-gonadal (HPG) axis and its influence on luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion. Gonadorelin is ideal for exploring hormonal regulation, fertility, and pituitary function.
Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH), a naturally occurring peptide that plays a critical role in regulating the reproductive endocrine system. It is primarily used in research to study the hypothalamic-pituitary-gonadal (HPG) axis and its influence on luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion. Gonadorelin is ideal for exploring hormonal regulation, fertility, and pituitary function.
GnRH is a decapeptide secreted by the hypothalamus that signals the anterior pituitary gland to release LH and FSH, two hormones essential to reproductive health and development. Gonadorelin mimics the natural GnRH peptide and has been used in clinical and research settings to assess pituitary responsiveness, stimulate gonadotropin production, and support hormonal balance.
Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabled as a drug, food or cosmetic.
What is Gonadorelin?
Gonadorelin (GnRH or LHRH) is a short peptide that activates GnRH receptors in the pituitary gland, triggering the release of LH and FSH. These hormones regulate reproductive processes such as ovulation in females and testosterone production in males. As a tightly controlled part of the HPG axis, GnRH pulses are essential to maintaining normal reproductive function. Gonadorelin’s pharmacological form allows researchers to observe and modulate this process with precision.
Key Functions and Benefits
Gonadotropin Stimulation: Increases LH and FSH levels, supporting reproductive hormone function.
Fertility Research: Useful in studies related to ovulation induction and male hormone regulation.
Pituitary Function Testing: Assesses responsiveness of the pituitary to hypothalamic signals.
Endocrine Balance: Helps explore regulatory dynamics within the HPG axis.
Delayed Puberty and Hypogonadism: Studied as a therapeutic tool for hormone deficiency conditions.
Mechanisms of Action
Gonadorelin binds to GnRH receptors on the anterior pituitary, triggering intracellular signaling cascades that lead to the release of LH and FSH. These gonadotropins then act on the gonads to stimulate the production of sex hormones (estrogen, progesterone, and testosterone) and regulate gametogenesis. Pulsatile administration mimics the natural secretion pattern of GnRH, which is key to sustaining proper hormonal feedback and reproductive health.
Unique Characteristics
Unlike other hormonal therapies, Gonadorelin works upstream by stimulating the body’s own hormonal cascade rather than replacing downstream hormones directly. This physiological approach provides a more accurate model for studying hormonal rhythms, dysfunctions, and regulatory feedback loops within the endocrine system.
Gonadorelin Peptide Structure
Source: PubChem
Sequence: Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly
Molecular Formula: C55H75N17O13
Molecular Weight: 1182.3 g/mol
PubChem CID: 638793
CAS Number: 33515-09-2
Synonyms:
ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.
The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat, or cure any medical condition, ailment, or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.
