


DSIP 5mg
Delta Sleep-Inducing Peptide (DSIP) is a naturally occurring neuropeptide studied for its role in promoting restful sleep, modulating stress response, and supporting central nervous system function. Originally isolated from the hypothalamus, DSIP is of interest for its regulatory effects on sleep cycles, hormonal balance, and neuroprotection. It is ideal for researchers exploring non-sedative sleep support and neuroendocrine modulation.
Delta Sleep-Inducing Peptide (DSIP) is a naturally occurring neuropeptide studied for its role in promoting restful sleep, modulating stress response, and supporting central nervous system function. Originally isolated from the hypothalamus, DSIP is of interest for its regulatory effects on sleep cycles, hormonal balance, and neuroprotection. It is ideal for researchers exploring non-sedative sleep support and neuroendocrine modulation.
Delta Sleep-Inducing Peptide (DSIP) is a naturally occurring neuropeptide studied for its role in promoting restful sleep, modulating stress response, and supporting central nervous system function. Originally isolated from the hypothalamus, DSIP is of interest for its regulatory effects on sleep cycles, hormonal balance, and neuroprotection. It is ideal for researchers exploring non-sedative sleep support and neuroendocrine modulation.
DSIP is a short peptide composed of nine amino acids and was first discovered in the 1970s in connection with slow-wave sleep regulation. Unlike traditional sleep aids, DSIP is believed to influence sleep architecture indirectly by modulating various neurohormonal systems rather than inducing sedation. Research suggests DSIP may help normalize circadian rhythms and support the body's adaptive response to stress.
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What is DSIP?
Delta Sleep-Inducing Peptide is present in both the central nervous system and peripheral organs. It appears to function as a neuromodulator, with effects on the hypothalamic-pituitary-adrenal (HPA) axis, stress hormones, and brain-derived neurotrophic factors. DSIP is being studied not only for its effects on sleep but also for its potential roles in reducing anxiety, improving mood, and supporting hormone regulation.
Key Functions and Benefits
Sleep Regulation: Supports the initiation and maintenance of deep (slow-wave) sleep without sedation.
Stress Modulation: May reduce cortisol levels and improve the body's resilience to stress.
Hormonal Balance: Has been observed to influence the secretion of luteinizing hormone (LH), growth hormone (GH), and ACTH.
Neuroprotective Effects: May protect neural tissue and enhance mood stability.
Mechanisms of Action
DSIP’s exact mechanism is not fully understood, but research indicates it acts as a neuromodulator with influence over multiple regulatory systems. It appears to modulate the release of several pituitary hormones and regulate activity in sleep-related centers of the brain. DSIP may also interact with GABAergic and opioid pathways, contributing to its calming and restorative effects.
Unique Characteristics
Unlike typical sleep aids or anxiolytics, DSIP does not cause sedation or cognitive dulling. Its naturally occurring structure and broad-spectrum regulatory activity make it an attractive candidate in research exploring holistic approaches to sleep disorders, stress adaptation, and hormonal health.
DSIP Peptide Structure

Source: PubChem
Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Molecular Formula: C35H48N10O15
Molecular Weight: 848.8 g/mol
PubChem CID: 68816
CAS Number: 69431-45-4
Synonyms: Delta Sleep Inducing Peptide
ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.
The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat, or cure any medical condition, ailment, or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.